Gene Mutation Raises Risk of Side Effects from Parasite Preventatives

by Lisa Selvaggio

Published: June 12th, 2024

According to findings from a recent study, over half a million cats in the U.S. should not be given certain parasite preventatives because they are at risk of serious adverse reactions. Pet parents who plan to use or currently use these products on their cats should inform themselves so they can make the right decisions for their pets’ health.

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The MDR1 Genetic Mutation and Parasite Preventatives

Researchers at Washington State University conducted a study that determined eprinomectin is an ingredient that can cause severe side effects in cats who have a genetic mutation known as MDR1. More specifically, it can cause a severe or fatal neurological reaction.

In cats with this genetic mutation, the drug is able to enter their brain, resulting in neurological toxicity. And, according to experts, reports of adverse reactions occur frequently even though the majority of cats do not have the MDR1 mutation. In fact, the team started their research in this area—which involved reviewing medical records of cats who got sick or died after being treated with eprinomectin—because of an increase in the number of reports of neurological reactions.

Symptoms of adverse reactions to eprinomectin typically develop hours after a product is applied to the skin. They include:

Increased salivation
Dilated pupils
Loss of coordination
Partial paralysis
Inability to retract or use the tongue
Seizures
Tremors
Coma
Death

Pet Parents Should Check Product Labels for Eprinomectin

Eprinomectin is an active ingredient in parasite preventatives like Centragard and NexGard COMBO. Cats with the MDR1 mutation should not be given any products containing eprinomectin.

Dr. Katrina Mealey led this research and is hoping that the U.S. Food and Drug Administration (FDA) will put warning labels on products that contain this ingredient. In the meantime, pet parents should check the labels of any products formulated to eliminate parasites like ticks, fleas, and worms to see if they contain eprinomectin.

If you aren’t sure if this ingredient is safe for your cat, talk to your veterinarian. Genetic testing can tell you if your cat has the mutation, and that information can guide your vet in determining which medications and parasite preventatives are safe for your kitty. Or, if you don’t genetically test your cat, you can play it safe by simply avoiding parasite preventatives that contain eprinomectin.

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Lisa Selvaggio

Lisa Selvaggio is a freelance writer and editor, and our resident cats-pert, with certifications in pet nutrition and pet first aid. She enjoys producing content that helps people understand animals better so they can give their pets a safe and happy home.

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Are Bengal Cats Really That Wild? Here's What Science Has to Say.

Bengal cats are a truly stunning feline breed, in many ways. According to the International Cat Association (TICA), they hold the title of being the most popular cat breed globally, and it doesn’t really come as a surprise. Their unique and exotic appearance, their unavoidable charm, and their slender physique are certainly the reason for this prestigious title. But even though they are popular, Bengal cats are a relatively new breed in the field of domesticated cats. While most ordinary domestic cat breeds have been around for thousands of years, Bengal cats have been around for less than a century, which comes as a stark contrast. They are a hybrid breed as well, having been created in the 1960s. They came about from the crossing of the domestic cat (Felis Catus), and the Asian Leopard cats (Prionailurus Bengalensis), which are a small, spotted, wild cat species living in Asia. What makes the combination unique is the fact that these two cat species had a common ancestor about 6 million years ago, which means that the genetic differences between them are incredible. The differences are even greater than between humans and chimpanzees!The resulting breed is the Bengal cat, and it is adored for its exotic appearance. It has special spots, just like ocelots or leopards. But most folks ascribe the unique coloration and patterns of these felines to the DNA they received from their wild and distantly related ancestors. And that’s why scientific folks paid special attention to the ancestry of Bengal cats. Greg Barsh, MD, Ph.D., Faculty Investigator at HudsonAlpha Institute for Biotechnology and Professor of Genetics at Stanford University,  himself an expert in the genetics of feline coat coloration and patterning is a key figure in the research process of Bengal ancestry. Together with his team, which is led by Chris Kaelin, Ph.D., and Kelly McGowan, MD, Ph.D., Mr. Barsh is working hard towards unraveling Bengal ancestry through the genetics of popular color traits."Cats are wonderful companions," he explains for  Phys.org, "but our interests go beyond their beautiful and exotic appearance. Like the amazing variation among different dog breeds, artificial selection can be a very powerful engine to create morphologic diversity. What's different about Bengal cats from dogs is the raw genetic material–dogs trace their heritage to wolves from tens of thousands of years ago.""In contrast, Bengal cats trace their heritage to completely different species from millions of years ago. Understanding how these distantly related genomes interact is a general question that applies to any situation when different species exchange genes, from crops to aquaculture to humans and Neandertals."And even though this is a relatively new breed, started about 60 years ago by a few cat enthusiasts, it has grown incredibly during this time. Today, there are hundreds of thousands of registered Bengal cats, which are produced by about 2,000 breeders. Chris Kaelin, the leader of the Bengal cat DNA study, said “Cat fanciers and breeders are very interested in the research, in part because they want to know more about the science behind artificial selection, and in part, because they want to know if our results can help them produce cats with rosettes, stripes, or other exotic markings.” He also added "This is a great example of citizen science–our work has been enabled by the willingness of breeders to participate, and we share our results with the community."One of the surprising discoveries that was produced from the study is that Asian Leopard DNA contributes no more than a few percent to the overall Bengal Cat DNA. In fact, it is revealed that there isn’t one or even a few Asian leopard genes that are causing the unique spotted Bengal appearance. "One of the original motivations for bringing together DNA from the two species was to select for Asian leopard DNA that would recapitulate the appearance of an exotic wild cat in a companion animal," said Kaelin. "It turns out that some of the most striking examples of selection in the breed are for traits that were already present, but very rare, in domestic cats."So, the study reveals that the Bengals are in many ways totally unique. Mixing the two very unique breeds resulted in a cat that is exotic, elegant, charming, and above all loveable. And now, the results published are providing valuable information to all the enthusiasts in love with the Bengal breed. 

Is It Safe For Dogs To Swim In The Ocean?

Most dogs are very capable swimmers. And many of them love to take a dip whenever possible. They might not like baths at home, but they will surely love to dive right into a lake, pond, or river. But what about those big bodies of water – lakes, seas, and more importantly, the ocean? These can be a bit scary and sometimes unpredictable, so owners are naturally apprehensive when it comes to their precious pet swimming in them. However, swimming in the ocean can be a fun and invigorating activity for dogs, offering them a chance to cool off, exercise, and explore a new environment. But even so, as a responsible pet owner, it's essential to understand the potential risks and take appropriate precautions to keep your furry friend safe. Here’s what you need to know before your pooch splashes around.Is It Safe For Dogs To Swim In The Ocean?While most dogs naturally enjoy splashing in the waves, the ocean presents unique challenges that require careful consideration. There are some important factors to keep in mind to ensure a safe and enjoyable ocean swimming experience for your dog and to fully enjoy your carefree days at the beach.Of course, it goes without saying that you should first observe the water and its surface, and to try and determine if it is safe to swim in. Ensure the water is clean and free of potentially harmful bacteria, algae, or pollutants. Avoid areas with red tides, dead fish, or signs warning of contamination. The next logical step is to consider the elements. If the weather is rough and the ocean seems “rowdy”, then it is best to avoid swimming. Be aware of the strength of its currents and waves that can be unpredictable. Strong undertows or large waves can be dangerous, especially for smaller dogs or less skilled swimmers. If your pet is not a proficient swimmer, you should make sure to get them a dog life jacket even when the water seems perfectly calm. Pick one in bright colors so your pet is easier to spot in case of an emergency – ideally with reflective details, too, for better visibility in low light conditions.

World’s Oldest Dog Posthumously Stripped of His Title

Last year, the world’s oldest dog was thought to be Bobi – who was reportedly  31 years old. However, a recent investigation into this claim led to him being posthumously stripped of the title by none other than Guinness World Records. The lofty title was suspended this January, as doubts rose about the dog’s reported age. Bobi lived in Portugal and sadly passed away last fall, and according to his owner, at a grand age of 31 years. However, a recent review by Guinness World Records revealed that they didn’t have the necessary evidence to support that claim."Without any conclusive evidence available to us right now, we simply can't retain Bobi as the record holder and honestly claim to maintain the high standards we set ourselves," Guinness Director of Records Mark McKinley said. "Of course, as with any record, we'll gladly assess any new evidence should we receive any."Before Guinness World Records actually grants a world record, they require ample evidence of a claim. Pictures, videos, statements from witnesses, documents, and anything similar are all required. And when pets are concerned, microchip data can also be examined. "Central to Bobi's evidence was microchip data sourced from the Portuguese government database, the SIAC, which it transpires, when chipped in 2022, did not require proof of age for dogs born before 2008," McKinley said. "With the additional veterinary statement provided as evidence for Bobi's age also citing this microchip data, we're left with no conclusive evidence which can definitively prove Bobi's date of birth."So, who is the real oldest dog in the world? Well, before Bobi’s lofty claim, there was the famous Bluey, an Australian cattle dog who held the record, being 29 years and 5 months old. But with these recent events, the future of this record will certainly change. McKinley claims that microchips need to be widely adopted around the world for serious claims to be made."Until that time, we'll require documentary evidence for all years of a pet's life, we'll continue to ask for vet and witness statements and we'll also consider microchip data as well where available," he added. "It's for this reason that we're not yet in a position to confirm a new holder for the record, although we certainly hope that the publicity around the record title encourages pet owners from around the world to get in touch."Sadly, Bobi died in October 2023, just months after celebrating what was reportedly his 31st birthday. He was a purebred Rafeiro do Alentejo, a native Portuguese dog breed that is known for its ability to protect livestock. These magnificent dogs have an average life expectancy of 12 to 14 years, and it was thought that Bobbi managed to live twice the time expected – but we’ll never know if that’s actually true or not.

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Study Shows These Dog Breeds Most Likely To Have an Extra Row of Teeth

Is your pooch more likely to sport a second row of teeth? The so-called “Shark Teeth” is a little-known dental condition that can affect up to 7% of doggos around the world. The “disorder” is officially known as persistent deciduous teeth (PDT) and it means that instead of falling out as you’d expect, baby teeth remain in the gums when adult teeth come through. The condition is not particularly dangerous, but even so, it can be odd or cause slight discomfort to a dog. Recent studies revealed that the dog breeds most likely to suffer from PDT are the Toy Poodle, the Yorkshire Terrier, the Maltese, and the Chihuahua. What exactly is PTD? And what does it cause? The disorder causes  malocclusion, or - in simpler terms - a misaligned bite. In the long run, this can cause your pet’s mouth to bleed, and also increase the risk of periodontal disease, which is considered a serious gum infection.The research team at the Waltham Petcare Science Institute in Leicestershire, led by Corrin Wallis, released their new study that focuses on PDT specifically. “Dogs use their teeth for a multitude of tasks and, as such, it is vital for their health and wellbeing that their oral health is maintained,” Wallis and colleagues  say.  “Persistent deciduous teeth (PDT), those that fail to fall out at the appropriate time, are associated with malocclusion (misaligned bite), soft tissue trauma and increased risk of periodontal disease.”In the course of their extensive study, which has been published in the journal  Research in Veterinary Science, the team from Leicestershire examined medical records from up to 2.8 million dogs in the US, in just a span of five years, from January 2010 to December 2014. The study itself was a major undertaking. Ultimately, it was revealed that the prevalence of PDT was 7%. When it comes to individual breeds, it was revealed that the highest prevalence is amongst the Yorkshire Terriers with 25.1%, followed by the Maltese and the Poodle, both with 14.8%.On the lower end of that spectrum, the lowest prevalence was with the Greyhound, with 0.1%, followed by the Rhodesian Ridgeback with 0.2%. Amongst those breeds with lower percentages were also the English Bulldog, the Boxer, and the Great Dane, with 0.4%. All of this reveals that the smaller the breed, the higher the percentage. The team is not certain why smaller breeds have a higher percentage, but it could be linked to their genetics. The team said that it was crucial for owners of smaller breeds to have a thorough oral examination at around six months of age. This can help them identify and remove PDT in its early stages. “Once identified, PDT can be removed and if this is carried out by six months of age, the chances of problems associated with PDT, such as the development of periodontal disease or malocclusion, can likely be greatly reduced,” they said. 

How to Get a Dog to Take a Pill

For most dogs, taking some form of pills – be it a supplement for preventing health issues or a medicine to treat existing ones – is a part of their daily routine. Sadly, that doesn’t mean that most dogs are used to the process and that they take the pill without protesting. Even though in most cases pills are not optional, our doggos often stubbornly refuse to ingest them. They’ll whimper, run, or straight out refuse to open their mouth. So how do you go about it and give a pill to your dog? Here are some useful tips and tricks that can make this task simple and quick!How to Get a Dog to Take a Pill – 5 Simple Tricks You Can Try Right NowOne of the best tricks you can use is to hide the pill in food. As we all know, most pooches are voracious and will gobble up anything you have in your hand. Any tasty treat will be quickly gulped down, with the hidden pill as well! In case you have a smart doggo on your hands, you can trick them by “accidentally” dropping some food with the pill hidden inside it and try to fake – prevent them from taking it – that works wonders for my spoiled poodle who’d eat anything if she thinks it’s forbidden. You can also try peanut butter, as it is sticky and flavorful, making it hard for the dog to detect the pill. Meat is great too, as dogs love it and it can hide a pill easily. If your dog is a picky eater or simply finds a way to get the pill out of the food every time you try to sneak it, you can also utilize  the specially designed pill pocket treats for dogs, which have a special hiding place for a pill. They’re irresistible too!

Can Dogs Get Pink Eye?

Eye issues are always a big nuisance, for both dogs and their owners alike. Conjunctivitis, commonly known as pink eye, is one of the more common ailments that affects the eyes and can happen to any of us. But can it affect dogs as well? Yes – conjunctivitis is quite common in dogs, and it causes red, inflamed eyes. In this case, it is called canine conjunctivitis. It can be caused by various factors including bacterial or viral infections, allergies, foreign objects in the eye, or other irritants, and it is manifested in several different ways – this is what you need to know if you suspect your pet has pink eye.Can Dogs Get Pink Eye?There are different types of conjunctivitis in dogs, and some are more dangerous than others. Either way, all dog owners should be well informed about all the potential issues that this inflammation can lead to, as well as the potential causes behind the different types of pink eye.Bacterial ConjunctivitisThis form of conjunctivitis in dogs is often characterized by a yellow or green discharge from the eye, along with redness and swelling of the conjunctiva, which is the thin, transparent membrane covering the inner surface of the eyelids and the white part of the eye. Bacterial conjunctivitis can be connected to other conditions such as respiratory infections or trauma.Viral ConjunctivitisCertain viral infections such as  canine distemper virus or canine adenovirus can also lead to conjunctivitis in dogs. These infections may cause watery discharge, redness, and inflammation of the eye. Viral conjunctivitis can sometimes be more challenging to treat and may require supportive care to manage symptoms.Allergic ConjunctivitisJust like us, dogs can also experience allergic reactions that affect their eyes. Common allergens such as pollen, dust mites, or certain foods can trigger allergic conjunctivitis in some dogs. Symptoms may include itching, redness, and watery discharge.IrritantsSometimes, foreign bodies and irritants in the eye can cause conjunctivitis. Things such as dust, sand, or grass can irritate the eyes and if not treated, lead to conjunctivitis. The same goes for certain airborne chemicals and smoke which can lead to further problems. Conjunctival HyperemiaSomewhat rare, this condition involves dilation of blood vessels in the conjunctiva membrane, resulting in redness of the eyes. It can be caused by various factors, including irritation, trauma, or systemic diseases.Treating and Preventing Pink Eye in DogsTreatment for canine conjunctivitis typically involves addressing the underlying cause. This may include topical or oral medications such as antibiotics for bacterial infections, antiviral drugs for viral infections, or anti-inflammatory medications for allergic reactions. In some cases, supportive care such as eye rinses or lubricating drops may be recommended to alleviate discomfort and promote healing.Of course, it pays to do anything you can to prevent the inflammation from occurring in the first place. Be wary of potential irritants and things that could hurt your dog’s eyes and lead to conjunctivitis. If you live in an area with plenty of dust, pollen, smoke, or anything similar, it might be wise to invest in  special protective gogg l es for dogs.

Is Your Cat Itchy? Causes and Treatments for Itching in Cats

Itching, or pruritis, in cats has various causes, so it’s a symptom of multiple problems. Sure, a cat will have an itch they need to scratch every now and then, just like people do. But if you see your cat scratching more than usual, or they’re scratching, licking, or biting themselves so much that they’re losing fur and causing cuts and scabs on their skin, there may be an underlying issue that should be addressed.Whether your cat is scratching at one area or they’re itchy all over, don’t ignore this problem. Read on to learn about some of the causes of itchiness in cats, along with some of the things you can do to provide relief. Remember, it’s always best to consult a veterinarian about your cat’s symptoms so you can give your pet the right treatment.Reasons Why Your Cat Is ItchyHere are some of the conditions that can cause a cat to feel itchy:AllergiesA lot of things can cause an allergic reaction in cats that leads to itchy skin. For example, if your cat is allergic to an ingredient in their food, such as a particular protein, their allergy might manifest as itchiness. As another example, your cat might be allergic to something in the environment, such as dust in the house or pollen that blows in through a window. And some cats have contact allergies to products, from litter to plastic or fabric, that can cause a reaction. The goal is to find the allergen and remove it from your cat’s environment as best as possible. In the case of a food allergy, using food trials with the guidance of your vet can help you figure out what’s causing the reaction so you can start giving your cat food that’s appropriate for them. ParasitesBites from insects and parasites can cause your cat to feel itchy. Fleas and mites are a couple examples. And, yes, indoor cats can get fleas, as they could be brought in from outside and find their way to your feline.When it comes to mites, such as ear mites or mange, your veterinarian can prescribe treatments after performing some tests for an accurate diagnosis.For flea allergy dermatitis caused by flea bites, it’s a matter of eliminating the flea infestation and preventing future infestations. You can use over-the-counter products, such as Frontline Plus for Cats, which is a topical treatment you apply between your cat’s shoulders (where they won’t be able to lick it off). It kills flea eggs, flea larvae, and adult fleas, as well as ticks and chewing lice, and each dose works for a month. But you also need to thoroughly clean your home and your pet’s things to be sure you eliminate fleas in the environment.

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The U.S. Postal Service Just Released Its National Dog Bite Rankings

Not all dogs are friendly and calm, and U.S. Postal employees know this all too well. Just in the last year, incidents involving dog attacks on Postal Service employees have risen to more than 5,800 cases. In an effort to raise awareness of these issues, the organization started the USPS 2024 National Dog Bite Awareness Campaign and is now offering key guidelines on how dog owners can help foster a better environment for safe mail delivery. Starting on June 2nd and running through June 9th, the campaign is running under the slogan “Don’t let your dog bite the hand that serves you.” Supporters can also spread awareness on social media, with the hashtag # dogbiteawareness.“Letter carriers are exposed to potential hazards every day, none more prevalent than a canine encounter. All it takes is one interaction for a letter carrier to possibly suffer an injury,” said Leeann Theriault, USPS Manager, Employee Safety and Health Awareness. “The U.S. Postal Service consistently encourages responsible pet ownership. The national dog bite campaign is an effort to promote dog bite awareness to keep our customers, their dogs, and letter carriers safe while delivering the mail.”Letter carriers are aware that dogs can be unpredictable, and even those who seem docile can bite unexpectedly. This is because doggos are usually protective of their home and are suspicious of strangers, even if they are just postal employees. They are now trying to emphasize the importance of dog owners ensuring safer mail delivery. As most people know the usual time a postman comes each day, it should be easier to secure their pets and minimize the risk of dangerous situations. When a postal employee comes to your home, try to keep your dogs inside the house or behind a secured fence, away from the door, or on a leash. Besides this, owners can now use Informed Delivery, a new and free USPS service, which allows customers to digitally preview any incoming mail and packages from their computer, tablet, or smartphone. Since the service launched in 2017, it garnered more than 52 million customers. Sign-up is possible at informeddelivery.usps.com. All dog owners can now anticipate the arrival of the postman and prepare accordingly. Dog bites can be harmful and costly too. Information from the Insurance Information Institute reveals that the average cost per insurance claim for a dog bite is $64,555. When a postal employee gets bitten, the owner can end up responsible for lost wages, medical bills, uniform replacement costs, and the pain and suffering that the employee endured.Of course, all postal employees are trained to observe an area where they know dogs are present. They have to remain alert and expect dangerous conditions. But also they have to respect a dog’s territory and their natural instinct. Overall, they are trained to never startle a dog, never attempt to pet or feed them, keep their eyes on the dog, and lastly to never assume a dog will not bite. They are also instructed to use a dog repellant if necessary and try to protect their vital areas.“Even though a customer’s dog is friendly to most people, it can always have a bad day,” said letter carrier Tara Snyder. “I know, from experience, even when a dog is in the house, customers need to make sure their door is secure so their dog can’t push it open and bite the letter carrier.”As a stark glimpse into the rate of dog bites on postal employees, a ranking was released as a part of this campaign. This lists the top 20 cities where dog bites occurred in 2023. Leading the list at number one is Los Angeles, with 65 attacks reported, followed by Houston and Chicago, with 56 and 58 attacks respectively. As for the states, the most reported attacks occurred in California, 727 in total. 

A Pennsylvania Dog Shocked Its Owners After Eating $4000 in Cash

A Pittsburg couple was shocked to discover that their dog Cecil decided to have the most expensive snack of his life, after wolfing down $4,000 in cash. According to Cecil’s owners, Clayton and Carrie Law, the seven-year-old goldendoodle is a well-behaved boy who has never really done anything bad before. The couple had withdrawn cash to do a home improvement project, but Cecil had other plans for the envelope full of money. Less than 30 minutes later, Cecil was caught devouring thousands of dollars. “I walked back into the room and then all this cash was on the ground. He’s just like this, standing there, and I’m like oh my gosh, he ate some of this money and was in shock. I yelled to Carrie ‘He ate the money, he ate the $4,000,’” said Clayton Law to CBS News. After the initial shock, the couple discovered that Cecil ate a lot of the bills, but that some were still on the floor, albeit torn up and chewed into pieces. Carrie and Clayton describe their pooch as laid back, weird, funny, and almost human-like, and say that he is typically more of a snuggly couch potato. “He doesn’t do many dog things, he doesn’t chew furniture or clothing, that’s why we were extra shocked when he decided to do this,” said Clayton Law. “He has never in his life tried to get anything from the counter, even coffee table. We could leave dinner and go to the kitchen and grab wine, and he would not touch the food, and he just doesn’t care. He just took this opportunity and ran with it,” said Carrie Law. Once the initial shock passed, the couple contacted their vet to see if the dog needed any treatment. Given the goldendoodle’s size, there was no risk of bowel obstruction and he only needed to be monitored at home. At first, Cecil seemed fine, but in the middle of the night, the Laws were awoken by the sound every dog owner knows - the retching of their dog about to vomit. “When you hear that, you immediately just react, so I jumped out of bed and just made sure that he didn’t throw up anywhere,” said Clayton. “And then I went to pick it up… and I realized there’s a lot of like half eaten and $100 bills and $50 bills here.”That night marked the start of the Law’s unfortunate mission of sifting through their dog’s vomit and poop in an attempt to recover some of their money. Luckily, the couple was able to piece together most of the bills after carefully washing and sorting all the pieces back together. “There we are at the utility sink washing this shitty money, yelling ‘Yay! Yes! We got one!’ It smelled so bad,” Carries confessed. After piecing together as many bills as they could salvage, the couple managed to recoup $3,550. According to Carrie, the bank was really nice about it and told them that these things happen all the time. “They said it actually happens quite a bit because money just picks up so many scents, especially if it’s used in the food industry. I guess dogs pick up on that - they have such a good sense of smell - and something about it just drove him crazy.”Almost a month after the incident, Cecil is doing fine and is still a good boy. Join the PetGuide community. Get the latest pet news and product recommendations by subscribing to our newsletter here.

Dog Helps Find Missing Child

Dogs can be heroes, and that’s certainly the case when it comes to the story of a very special police K9 in Auburn, Massachusetts. When a 12-year-old went missing from their home and couldn’t be found for roughly two hours, Auburn police knew that they had to work quickly, and Biza the dog played an integral role in the child’s rescue.Child Found with the Help of a Police K9 Named BizaAccording to a Facebook post by Auburn MA Police Department, information about a missing child was received around 10:30 p.m. on January 31, 2024. The child had been missing since around 8:30 p.m., when they had left their home. No one knew where the child could be, and the frigid temperatures made everyone worry even more about their safety.Because the child had last been seen in the Pakachoag Hill area, Auburn police officers, Massachusetts State Police troopers, and detectives got to work looking for them. But it would be Biza, the K9 partner of Officer Ljunggren, who would really come through and help the search end successfully that night.Following the Scent to a Missing ChildBiza picked up the child’s scent and tracked it for more than two miles. The police were able to find signs that the missing child had been in the area, so they kept up the search until they were able to find them and bring them home to their family just a short while later.This is one example of many times that Biza has helped police in Auburn succeed since she joined them in 2022 from Germany. In addition to helping find missing people, she has also helped police track down suspects.  Thanks to Biza and her ability to track the right scent that night, a child was saved from the cold and made it home safe.Here’s a quick video about this story, showcasing a few photos of beautiful Biza:

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This US Map Reveals Which States Prefers Dogs Over Cats And Vice Versa

The age-old question: who is more popular, cats or dogs? Some owners will staunchly defend their doggos as the best pets around, while others won’t budge a from claiming their cherished felines should be #1. But what do the statistics say? An interesting survey unveiled a special map of the U.S. : one that shows us exactly the differences in cat and dog popularity.State by state, percentage by percentage, the cat and dog battle is revealed in accurate numbers, thanks to the website Zippia. A truly stunning graphic map has been published by this website otherwise known as a popular career and job portal. And it reveals each U.S. state’s choice of pets. First, however, we need to understand that roughly 86.9 million homes in America (around 66%) owns a pet in 2023-2024, according to the American Pet Products Association (APPA). And from these numbers, it is revealed that around 65.1 million homes own a dog, making them by far most popular choice of pet animal. In comparison, around 46.5 million homes own a cat. But still, many of these owners own both a cat and a dog.But the Zippia map shows exactly which states are majority doggo lovers, and which ones are strictly feline fans. Their results were compiled with detailed data from the Bureau of Labor Statistics, the American Veterinary Medical Association, and the American Kennel Club.The numbers tell us that Arkansas is the state that has the most dog lovers in the entire country - around 48% of its residents own a dog according to Zippia. A stark contrast is Massachusetts, with just 24% of its residents owning a pooch. And then there are the cat fans. According to Zippia, the most feline-friendly states are Maine, Massachusetts, and Vermont. This reveals that America’s northeast has a special tendency towards cats in general. Some readers suggested that the climate and the general ambience of New England is more favorable for cats rather than doggos. But northernmost and southernmost states, Alaska and Texas, are strict doggo fans, which may be connected with their rugged nature and the protective and work role of certain dog breeds. But what about the breeds? Zippia also reveals that most states, 45 in total, are absolutely mad about Labrador Retrievers. This should not come as a surprise - Labradors are gentle and caring animals that make great pets. What about you? Are you a dog lover or a feline friend? Or do you adore both? 

Can I Teach My Hamster to be Quiet at Night?

Have you ever scrolled social media to find viral videos of hamsters running enthusiastically on their exercise wheel? There is no denying that it’s an adorable sight! Unfortunately, it becomes far less cute for hamster parents when their nighttime playtime keeps us awake all night.If you’re wondering if there’s a way to train your hamster to adjust to a more human sleep cycle, you’re not alone.In this post, I will share some key information about hamsters and their sleep habits, including why your hamster is so active when the sun goes down. Plus, I’ll share tips and tricks to create a happy home for both you and your hamster – including gear that has helped me coexist peacefully with my hamsters over the years.With a few minor changes or updates, you can share your life with a hamster and enjoy a good night’s sleep. I promise! Why is My Hamster So Active at Night? Since bringing your hamster home, you may have noticed that they are most active at night, catching up on their sleep throughout the day. If you’ve been searching for answers (which you probably are, if you’re reading this), you may have seen many people explaining that you’re experiencing this schedule because hamsters are nocturnal – meaning they are active at night and sleep during the day. However, this isn’t entirely accurate. Hamsters are actually crepuscular. This means that (according to Cambridge Dictionary), they are “active or appearing at the time of day just before the sun goes down, or just after the sun rises, when the light is not bright.” With pet hamsters, this is often mistaken as nocturnal because we are asleep during that period between dusk and dawn. Therefore, we don’t experience them slowing down or resting during the middle of the night. Returning to the original question: “Why is my hamster so active at night?” The short answer is this behavior is the result of their biological wiring. In the wild, they are active when it is safer to emerge and seek out food. This allows them to hide when predators are more likely to see them in the daylight hours. Are All Hamsters Active at Night? As with any behavior, there are always going to be exceptions. If you were to interview 100 hamster parents, you are likely going to find one or two that “break the rules” and are active during the day. However, this is rare. It’s safe to assume that any hamster you adopt and bring home will be most active at dusk and dawn, not during the daylight hours. Can You Change a Hamster’s Sleep Schedule?It is possible to change a pet’s sleep cycle. However, there is no guaranteed approach that will work with every hamster. It’s also not recommended by experts as this process could cause significant stress and anxiety to your hamster by forcing them to go against their instincts. Rather than changing your new pet’s sleep schedule, it’s recommended that you instead focus on making changes to their habitat to accommodate their natural sleep pattern. Does this mean your hamster will always be active at night? Not necessarily. Over time, you may see your hamster adjusting their sleep schedule to better align with your schedule without trying to make a change yourself. But it should not be forced on them. Influencing Your Hamster’s Sleep Schedule While it’s not recommended that you train your hamster to completely change their sleep schedule, you can take steps to influence it and encourage them to adjust slightly to your routine. The best approach to influencing your hamster’s sleep schedule is to encourage them to stay awake and play when they are already awake, not waking them up if they have fallen asleep. Hamsters are startled easily due to their poor eyesight, which means waking them up could trigger severe anxiety. If your hamster is awake at a time that suits your schedule and routine, take the opportunity to spend quality time together while encouraging them to stay awake longer. This could mean playing with them or giving them lots of affection if they are tame and like to be handled. This should be done gradually, keeping them awake just a little longer each day. As you encourage these changes, watch carefully for any signs of stress and anxiety, such as: Loss of appetite Refusing to drink water Increased vocalizationHiding constantly, especially during hours when they are usually activeLethargy or loss of energyFailing to chew and wear down their teeth, overgrown teethChewing at the cage bars Hair loss, bald spots, overgroomingObsessive behaviors like digging, scratching, or lickingUncharacteristic aggressionIf you notice any of these signs, take a step back. This could indicate that you’re pushing your hamster to make changes too quickly or that they aren’t comfortable changing their sleep schedule at all. Reevaluate your efforts and make a decision that prioritizes their quality of life. If that means abandoning this attempt and focusing instead on changing their habitat to minimize noise, that may be the best solution for everyone.

Drug That Could Extend Lifespan of Senior Dogs Enters Clinical Trial

A new and revolutionary drug that could possibly extend the lifespan of healthy, senior dogs, is now entering a major clinical trial. It also has a first patient - an 11-year-old Whippet named Boo. Going by the codename LOY-002, this drug is designed to provide a few more years to senior dogs of most sizes. It is the product of a startup biotech company called  Loyal and is the fruit of their hard work and arduous research. Celine Halioua, the founder and CEO of Loyal, said that the company is working hard to develop several products aimed at the longevity of dogs. One of their initial projects, the LOY-001, was a drug aimed to extend the lifespan of giant and large dog breeds. In November of 2023, this project received the support of the FDA, paving the way for the company's further successes. The underlying mechanisms of aging were the first focus of the company as it developed LOY-001. The drug works by reducing IGF-1, an insulin-like growth factor that is a key biomarker hormone that drives cell growth. It is believed that this reduced the lifespan of extra-large dogs. Similarly, the LOY-002 project aims to extend the lifespan of normal-sized dogs, by improving their metabolic health and thus delaying the onset and the impact of diseases that come with old age. “LOY-002 is a slightly different mechanism [than LOY-001] for senior lifespan extension. It’s a little bit more of a reversal mechanism. It’s not going to make a 10-year-old dog a puppy, but we’ve seen a rescuing in age-related functional decline in dogs that have been treated with this drug,” said Halioua in an interview with  dvm360.The newest study for LOY-002 is expected to last 4 years, and include one thousand enrolled dogs. “It will be one of the largest veterinary clinical studies that, as far as we know, has ever been run,” added Halioua.The first ever receiver of the drug, Boo, was enrolled into the program in Harrisburg, Pennsylvania, at the Animal Hospital of Dauphin County. There, an associate veterinary and STAY study investigator, Coby Rudakewiz, became a part of the program for the first time, witnessing its incredible potential. “I’m genuinely excited to be able to share what we’ve seen as a life-changing product to dogs of all sizes,” he said.“This is what it’s all about - keeping dogs feeling their best to enjoy a long life with their owners who love them.”“The launch of this study brings us one step closer to helping senior dogs have more, healthier years with their families…The scale and complexity of STAY reflect Loyal’s commitment to creating demonstrably effective and safe products,” Halioua added. “This is a massive undertaking that wouldn’t be possible without the partnership of the many veterinarians and technicians operating the study in their clinics, and the participating dogs and owners helping advance therapies for all dogs.”For the time being, the company is working hard to receive conditional approval for its revolutionary drug. This would allow them to begin offering it through veterinarians as soon as 2025. This could mean a world of difference for many senior doggos and their families. Seeing your senior doggo enjoy a few extra years without the issues common to old age is nothing short of true happiness, and would mean that the company’s hard efforts were not in vain. Ultimately, this innovative drug gives us hope for the future and makes us wonder what other ground-breaking drugs could we see in the years ahead.

How Cold is Too Cold for My Dog to Be Outside?

You might enjoy the magic of wintertime, but that doesn’t mean that your pooch shares your enthusiasm for cold weather – or the situation might be the exact opposite, with your four-legged bestie enjoying snowfall and you dreading the icy temperatures. Either way, you might be wondering if your pet needs some extra protection or different routines during winter – after all, some dogs are less suited for cold than others. So, it begs the question how cold is too cold for your dog, and should you even try going outside in these cases? There are several precautions you can take, but sometimes, you should be wary of extreme temperatures. Let’s delve deeper and learn more. How Cold is Too Cold for My Dog to Be Outside?The tolerance to cold weather can vary among individual dogs based on factors such as breed, size, coat type, age, and overall health. Generally, most dogs can tolerate cold weather to some extent, but there are certain conditions and temperatures where it becomes unsafe for them to be outside for extended periods. Of course, there will be some telltale signs that it’s just too cold to be outside. Signs that your dog may be too cold include shivering, whining, seeking shelter, lifting paws off the ground, or exhibiting signs of discomfort. If you notice any of these signs, it's time to bring your dog inside for some much-needed warmth.Of course, it’s essential to use your judgment and consider your dog's individual needs – you should always prioritize your dog's well-being in extreme weather conditions, but that will differ from dog to dog and climate to climate. Even so, there are some general guidelines for determining if it’s too cold outside for your pet – here’s what you need to know before taking them outside in really cold weather.Consider their coat length and breed: In winter, your pet’s coat can be a determining factor for outside time. Dogs with thick or double coats, such as  Siberian Huskies or  Alaskan Malamutes, may be more tolerant of cold temperatures than those with short coats, like Chihuahuas or Greyhounds. Some dogs were specially bred for living and working in cold environments, while some breeds were developed for completely opposite conditions. If your pet belongs to the latter group, it might be useful to invest in  a warm coat  designed to keep your dog toasty and warm during cold weather.

Which Spring Flowers Are Toxic to Dogs?

Springtime is such a joyful time of the year. The harsh and gloomy winter days are finally over, and nature is awakening – the sun is shining, trees are blooming, and life erupts all over again. But that doesn’t mean that there are no downsides to this season. From spring allergies to spring shedding, there are also quite a few things that don’t spark joy when spring comes. One of those unexpected things that become a downside of spring when you’re a dog is flowers. Yup. Those gorgeous, lush-smelling blooms that appear in the spring can pose a threat to your dog, as many spring flowers are toxic to our canine friends.So without further ado, let’s see which of these pretty, colorful flowers are potentially dangerous for dogs – so you’ll know exactly which of them to avoid planting in your garden or putting in a vase.Which Spring Flowers Are Toxic to Dogs?As we all know, dogs are inquisitive and love to nibble and sniff all sorts of odd things, flowers included. This is why you should be vigilant in the spring when many potentially toxic plant varieties are in season. Keep an eye out for the following flowers when walking your pet out and about or when picking out seeds for your flower beds!Daffodils

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