A Clinical Study of GLP-1 for Cats Is Being Conducted at Cornell

Lisa Selvaggio
by Lisa Selvaggio

Keeping your cat at a healthy weight can help them stay well, and if your veterinarian determines that your kitty needs to lose some weight to be healthier, it’s best to follow their guidelines for safe weight loss.


You might’ve seen recent headlines about the possibility of an Ozempic style option being made available for pets. Well, now there’s a clinical study being conducted at Cornell University College of Veterinary Medicine to see if a GLP-1 therapy can indeed work on cats.

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Akston’s Clinical Study at Cornell University


Akston is a biotech company focused on pets. They launched a clinical trial in late November 2025, stating that they were screening their first cats, and were planning on enrolling a total of 70 kitties, with the potential of working with 140 cats. 


The goal of the clinical study is to test Akston’s next-generation GLP-1 protein. It is a weight management therapy that they made for cats who need to lose weight, and it works by regulating appetite so kitties eat less and shed excess pounds. It’s meant to be used alongside other weight loss strategies like nutritional management.


The therapy, known as AKS-562c, is an Fc-fusion GLP-1 candidate. It’s given once a week, and the trial will assess how it works over 11 weeks, or roughly three months. Client-owned domestic cats who are overweight will be involved.


Preclinical studies that were done at Cornell University involved laboratory cats. Researchers found that this GLP-1 therapy didn’t cause adverse effects. The current trial will closely monitor the effects in client-owned cats to determine if the weight loss therapy is well-tolerated, effective, and safe.


Tackling the Problem of Feline Obesity


Experts want to find a safe way to address feline obesity, which is common among cats but can be hard to treat effectively. Excess weight could increase the risk of health problems, such as orthopedic conditions like osteoarthritis and diseases like diabetes, so keeping your cat’s weight within an optimal range is important for their overall wellness and longevity.


Stay tuned for news about the results of Akston’s clinical study, and also keep an eye out for news about their GLP-1 for dogs. 


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Lisa Selvaggio
Lisa Selvaggio

Lisa Selvaggio is a freelance writer and editor, and our resident cats-pert, with certifications in pet nutrition and pet first aid. She enjoys producing content that helps people understand animals better so they can give their pets a safe and happy home.

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