Research Shows Telomir-Zn Might Slow Bone Cancer in Dogs
Researchers have discovered that a drug, Telomir-Zn, might be useful against bone cancer in dogs, but more studies will need to be completed to confirm its effectiveness. Check out the information below to learn about the preclinical testing that has provided some hope in this important area of dog health.
Telomir-Zn, developed by Telomir Pharmaceuticals, is an experimental cancer drug that showed promise against both human and canine osteosarcoma in preclinical testing at The Ohio State University. The drug worked on slowing the growth of cancer cells in in-vitro lab tests that were completed at the university’s College of Veterinary Medicine.
Promising Research That Could Benefit People and Dogs
The study involved testing Telomir-Zn on three osteosarcoma cell line models, two of which were canine lines and one which was a human line. All of the lines exhibited inhibition of cancer growth at low drug concentrations. This provides quite a bit of hope because there aren’t many treatment options for dogs who are diagnosed with osteosarcoma.
Telomir-Zn affects how cells regulate copper and iron, and because there are several similarities between osteosarcoma in humans and in dogs, the treatment might be a good option for both species.
Next Step: More Research
In dogs, osteosarcoma is one of the most common types of bone cancer. It also causes most of the primary bone tumors in large breeds. Because of the poor outcomes associated with this disease, any progress towards finding treatments is great news for pet parents and veterinarians.
Because of the drug’s effectiveness at inhibiting cancer growth in-vitro, the next possible step may be to run in-vivo tests, with experts trying the drug on dogs with naturally occurring osteosarcoma to determine if it works as well as it did in-vitro.
The best part is that, in addition to helping dogs, this type of research could also be used to help humans with the same type of cancer, so it will be exciting and interesting to see what future studies show.
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Lisa Selvaggio is a freelance writer and editor, and our resident cats-pert, with certifications in pet nutrition and pet first aid. She enjoys producing content that helps people understand animals better so they can give their pets a safe and happy home.
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