A New Cancer Drug Shows Promise for Both Cats and People

Lisa Selvaggio
by Lisa Selvaggio

A new drug may be used for treating cancer—more specifically, oral squamous cell carcinoma—according to a clinical trial conducted by researchers in California. Keep reading to learn a bit about this promising treatment and how it might help cats and humans.

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Oral Squamous Cell Carcinoma: A Difficult Cancer to Treat


Thanks to researchers at the University of California, Davis and the University of California, San Francisco, there might be some hope for feline patients who have been diagnosed with oral squamous cell carcinoma.


This is an aggressive type of cancer, and cats who develop it typically live only a few months. Current options like chemotherapy, radiation, and surgery aren’t effective at stopping this cancer’s growth, so there’s very little that can be done to help the cats, who inevitably end up dying from this terrible disease.


A Clinical Trial with Promising Results


The drug, referred to as cyclic STAT3 decoy (CS3D), works by targeting STAT3, a protein that causes cancer cells to grow. It also helps increase a protein that’s linked to the immune system’s response to the disease. When it was given to cats with squamous cell carcinoma, it controlled the disease in 35% of them.


A total of 20 cats were enrolled in the clinical trial, and the drug didn’t cause any side effects aside from mild anemia. During the study, seven of the kitties had stable disease or experienced a partial response to the drug. Their average survival time after the treatment was 161 days.


A cat named Jak is a good example of improved survival time with CS3D. His owners were originally told he’d live six to eight weeks, but he lived more than eight months after receiving treatments for a month as part of the clinical trial.    


In addition to combating cancer in cats, this drug may also be useful in cases of head and neck squamous cell carcinoma in humans.   


These types of studies can help experts find solutions for both people and pets, so they are planning on doing more research and clinical trials to gain even more insight into what’s possible.  


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Lisa Selvaggio
Lisa Selvaggio

Lisa Selvaggio is a freelance writer and editor, and our resident cats-pert, with certifications in pet nutrition and pet first aid. She enjoys producing content that helps people understand animals better so they can give their pets a safe and happy home.

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